How to keep the skin healthy and white is a very important issue, and the research and development of high safety and whitening effect of skin care products has been the dream of cosmetic formula designers. Skin color is largely determined by the formation, migration, and distribution of Melanin. At present, the research on whitening and freckle is focused on tyrosinase. TYROSINASE is a very common amino acid in human body. In melanocyte melanosomes, tyrosinase catalyzes tyrosinase to produce DOPA, and DOPA quinone is formed after dehydrogenation of DOPA, and rearranged into 5,6-hydroxyindole, Indole polymerization and the structure of the protein combined with melanosomes melanoproteins, melanoproteins that we commonly referred to as Melanin.
Serial number
Test Ite
Detection model
Detection Index
Whitening
Expression of genes involved in Melanin
Synthesis and operatio
Melanin conten
Inhibition of Tyrosinase activity-biochemical
experimen
Free radical scavenging ability
Inhibition of Tyrosinase activity-cell
experiment
A sample test concentration (%)
B sample test concentration (%)
Combined with MTT Cytotoxic morphological observation, the safe concentration of the sample is less than 0.25%